Chemistry of Biomolecules I

Image showing the multi-colored coils of shikimate kinase.

Crystal structure of shikimate kinase. (Image courtesy of the RCSB PDB. PDB ID: 1VIA. Badger, J., et al. "Structural analysis of a set of proteins resulting from a bacterial genomics project." Proteins 60 (2005): 787-796.)


MIT Course Number


As Taught In

Fall 2005



Cite This Course

Course Description

Course Features

Course Description

5.451 is a half-semester introduction to natural product biosynthetic pathways. The course covers the assembly of complex polyketide, peptide, terpene and alkaloid structures. Discussion topics include chemical and biochemical strategies used to elucidate natural product pathways.

Related Content

Sarah O’Connor. 5.451 Chemistry of Biomolecules I. Fall 2005. Massachusetts Institute of Technology: MIT OpenCourseWare, License: Creative Commons BY-NC-SA.

For more information about using these materials and the Creative Commons license, see our Terms of Use.