Projects in Microscale Engineering for the Life Sciences

People in cleanroom suits view magnified wafer pattern on screen.

Members of the class inspect one of the wafers they created in lab. (Image courtesy of A. Aranyosi.)


MIT Course Number

HST.410J / 6.07J

As Taught In

Spring 2007



Cite This Course

Course Description

Course Features

Course Description

This course is a project-based introduction to manipulating and characterizing cells and biological molecules using microfabricated tools. It is designed for first year undergraduate students. In the first half of the term, students perform laboratory exercises designed to introduce (1) the design, manufacture, and use of microfluidic channels, (2) techniques for sorting and manipulating cells and biomolecules, and (3) making quantitative measurements using optical detection and fluorescent labeling. In the second half of the term, students work in small groups to design and test a microfluidic device to solve a real-world problem of their choosing. Includes exercises in written and oral communication and team building.

Related Content

Dennis Freeman, Martha Gray, and Alexander Aranyosi. HST.410J Projects in Microscale Engineering for the Life Sciences. Spring 2007. Massachusetts Institute of Technology: MIT OpenCourseWare, License: Creative Commons BY-NC-SA.

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