Principles and Practice of Drug Development

Two dose-response curves showing different amounts of a drug on the x-axis, and effect on the body on the y-axis. The resulting curves for "desired effect" and "side effect" both have a steep slope with a slight "S" shape before leveling off at the top.

An example of a dose-response curve which shows how much of a drug causes a particular effect or side effect in the body (Crabtree + Company, National Institute of General Medical Sciences).


MIT Course Number

15.136J / IDS.620J / 7.547J / 10.547J / HST.920J / (formerly ESD.691J)

As Taught In

Fall 2013



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Course Description

Course Features

Course Description

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

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Related Content

Charles Cooney, Stan Finkelstein MD, G. Raju, and Anthony Sinskey. 15.136J Principles and Practice of Drug Development. Fall 2013. Massachusetts Institute of Technology: MIT OpenCourseWare, License: Creative Commons BY-NC-SA.

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