Systems Biology

A neutrophil, shown as a large irregularly-shaped blue-gray cell, wrapping around pink oval-shaped Klebsiella pneumoniae bacteria.

A neutrophil (a type of white blood cell, shown in blue-gray) interacting with Klebsiella pneumoniae bacteria (shown in pink). This is one example of the types of functions that Systems Biology seeks to understand and describe. Watch Lecture 1 to see a video of a neutrophil chasing and engulfing a bacterium. (Image by NIAID, CC-BY.)



MIT Course Number

8.591J / 7.81J / 7.32

As Taught In

Fall 2014


Undergraduate / Graduate

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Course Description

Course Features

Course Description

This course provides an introduction to cellular and population-level systems biology with an emphasis on synthetic biology, modeling of genetic networks, cell-cell interactions, and evolutionary dynamics. Cellular systems include genetic switches and oscillators, network motifs, genetic network evolution, and cellular decision-making. Population-level systems include models of pattern formation, cell-cell communication, and evolutionary systems biology.

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Related Content

Jeff Gore. 8.591J Systems Biology. Fall 2014. Massachusetts Institute of Technology: MIT OpenCourseWare, License: Creative Commons BY-NC-SA.

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