Principles of Pharmacology

Glass vials and bottles containing chemotherapy drugs.

Chemotherapy drugs in vials and an IV bottle. (Photo by Bill Branson. Courtesy of National Cancer Institute Visuals Online.)


MIT Course Number


As Taught In

Spring 2005



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Course Description

Course Features

Course Description

The object of the course is to teach students an approach to the study of pharmacologic agents. It is not intended to be a review of the pharmacopoeia. The focus is on the basic principles of biophysics, biochemistry and physiology, as related to the mechanisms of drug action, biodistribution and metabolism. The course consists of lectures and student-led case discussions. Topics covered include: mechanisms of drug action, dose-response relations, pharmacokinetics, drug delivery systems, drug metabolism, toxicity of pharmacological agents, drug interaction and substance abuse. Selected agents and classes of agents are examined in detail.


Prof. Keith Baker

Dr. Mark Dershwitz

Harold Demonaco

Dr. Daniel Kohane

Dr. Donald Kufe

Prof. Robert Langer

Dr. Robert Lees

Dr. Robert Rubin

Dr. Jeremy Ruskin

Prof. Thomas Spitzer

Prof. Carol Walsh

Dr. Michael Weinblatt

Dr. Warren Zapol

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Related Content

Carl Rosow, David Standaert, and Gary Strichartz. HST.151 Principles of Pharmacology. Spring 2005. Massachusetts Institute of Technology: MIT OpenCourseWare, License: Creative Commons BY-NC-SA.

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