Biological Chemistry II

Structural image of protein complex from PDB database.

The Structure Of Beta-Ketoacyl-[Acyl Carrier Protein] Synthase I In Complex With Thiolactomycin, Implications For Drug Design. PDB ID: 1FJ4.  Price, A. C., Choi, K., Heath, R. J., Li, Z., White, S. W., Rock, C. O.: Inhibition of Beta-Ketoacyl-[Acyl Carrier Protein] Synthases by Thiolactomycin and Cerulenin: Structure and Mechanism J.Biol.Chem. 276 pp. 6551 (2001). (Image courtesy of the Research Collaboratory for Structural Bioinformatics.  H.M.Berman, J.Westbrook, Z.Feng, G.Gilliland, T.N.Bhat, H.Weissig, I.N.Shindyalov, P.E.Bourne The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000).)


MIT Course Number

5.08J / 7.08J

As Taught In

Spring 2004



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Course Description

Course Features

Course Highlights

The tools section includes information about various molecular graphics programs used to view three-dimensional structures in this course.

Course Description

This course deals with a more advanced treatment of the biochemical mechanisms that underlie biological processes. Emphasis will be given to the experimental methods used to unravel how these processes fit into the cellular context as well as the coordinated regulation of these processes. Topics include macromolecular machines for energy and force transduction, regulation of biosynthetic and degradative pathways, and the structure and function of nucleic acids.

Related Content

JoAnne Stubbe, and Alice Ting. 5.08J Biological Chemistry II. Spring 2004. Massachusetts Institute of Technology: MIT OpenCourseWare, License: Creative Commons BY-NC-SA.

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