Computational Functional Genomics

Diagrams of the genetic transcription process.

Three steps in the transcription of protein-coding genes. (Image by Prof. David Gifford.)


MIT Course Number

7.90J / 6.874J

As Taught In

Spring 2005



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Course Description

Course Features

Course Description

The course focuses on casting contemporary problems in systems biology and functional genomics in computational terms and providing appropriate tools and methods to solve them. Topics include genome structure and function, transcriptional regulation, and stem cell biology in particular; measurement technologies such as microarrays (expression, protein-DNA interactions, chromatin structure); statistical data analysis, predictive and causal inference, and experiment design. The emphasis is on coupling problem structures (biological questions) with appropriate computational approaches.

Related Content

David Gifford, and Tommi Jaakkola. 7.90J Computational Functional Genomics. Spring 2005. Massachusetts Institute of Technology: MIT OpenCourseWare, License: Creative Commons BY-NC-SA.

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