Experimental Molecular Genetics

 A magnified view of the roundworm C. elegans, appearing as a U-shaped curve, and stained in red.

C. elegans viewed under a microscope, with cell nuclei stained in red.  C. elegans is used as the model system to teach chemical genetics in 7.15, and is also used as a model organism in many areas of biological research. Actual size of adult organisms is around 1 mm long. (Image by Quadell, Wikimedia Commons, CC-Attribution license.)


MIT Course Number


As Taught In

Spring 2015



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Course Description

Course Features

Course Description

This project-based laboratory course provides students with in-depth experience in experimental molecular genetics, using modern methods of molecular biology and genetics to conduct original research. The course is geared towards students (including sophomores) who have a strong interest in a future career in biomedical research. This semester will focus on chemical genetics using Caenorhabditis elegans as a model system. Students will gain experience in research rationale and methods, as well as training in the planning, execution, and communication of experimental biology.


The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented.

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Related Content

Jing-Ke Weng, and Nelly Cruz. 7.15 Experimental Molecular Genetics. Spring 2015. Massachusetts Institute of Technology: MIT OpenCourseWare, https://ocw.mit.edu. License: Creative Commons BY-NC-SA.

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